Viscoelastic behavior of calcium phosphate packed bacterial cellulose -polyvinylpyrrolidone based hydrogel scaffolds at human fever temperature

Probal Basu, Nabanita Saha, Oyunchimeg Zaandra, Petr Saha

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Calcium phosphate (CaP) packed bacterial cellulose (BC) and polyvinylpyrrolidone (PVP) based hydrogel scaffolds (BC-PVPCaP) are being reported here considering its possible application in bone restoration. The primary focus of this work is to analyze the viscoelastic behavior of 'BC-PVP-CaP' hydrogel scaffolds at human fever temperature condition (39°C) in swelled state. In BC-PVP scaffolds, CaP [in the form of β-tricalcium phosphate (β-TCP) and hydroxyapatite (HA) is present as filler in different concentrations (i.e. β-TCP/HA_20:80, β-TCP/HA_40:60, β-TCP/HA_50:50). The BC-PVP scaffold (without CaP) was marked as a control set for the evaluation of viscoelasticity of scaffolds. The BC-PVP-CaP_50:50 hydrogel scaffold showed the highest degree of swelling at 39°C among the other BC-PVP-CaP scaffolds. However, the other hydrogel scaffolds were also showed notable viscoelasticity at 39°C. Experimental results confirmed that the CaP filled BC-PVP hydrogel scaffolds (BC-PVP-CaP_20:80, BCPVP- CaP_40:60, BC-PVP-CaP_50:50) exhibit a promising viscoelastic behavior at human fever temperature condition (39°C), can be endorsed for its potential application in bone repairing /bone restoration.

Original languageEnglish
Title of host publicationProceedings of PPS2019, Europe-Africa Regional Conference of the Polymer Processing Society
EditorsSuprakas Sinha Ray
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735440197
DOIs
Publication statusPublished - 26 Nov 2020
EventPPS Europe-Africa 2019 Regional Conference, PPS 2019 - Pretoria, South Africa
Duration: 18 Nov 201922 Nov 2019

Publication series

NameAIP Conference Proceedings
Volume2289
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

ConferencePPS Europe-Africa 2019 Regional Conference, PPS 2019
Country/TerritorySouth Africa
CityPretoria
Period18/11/1922/11/19

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