Transient Increase in X-ray-induced c-Jun, c-Fos and BRCA1 Expression by Exposure to Power Frequency Magnetic Fields in MCF-7 Cells

Furong Tian; Takehisa Nakahara; Junji Miyakoshi

Transient Increase in X-ray-induced c-Jun, c-Fos and BRCA1 Expression by Exposure to Power Frequency Magnetic Fields in MCF-7 Cells

Furong Tian, Takehisa Nakahara, Junji Miyakoshi

Research output: Contribution to journal › Article › peer-review

Abstract

The effects of Extremely Low Frequency Electromagnetic Fields (ELFMF, 50 Hz,
5 mT) and/or X-rays on the expression of the BRCA1, p21, c-Myc, c-Jun and c-Fos proteins were investigated in human breast adenocarcinoma MCF-7 cells. A transient increase of c-Jun and c-Fos was observed after either ionizing radiation or magnetic field exposure. We found that ELFMF increased the X-ray-induced expression of BRCA1, p21 and c-Myc. These findings demonstrate that ELFMF can modify gene expression.

Original language	English
Pages (from-to)	123-128
Journal	Bulletin of Health Sciences Hirosaki Vol. 4
Publication status	Published - 2005
Externally published	Yes

Cite this

@article{dca71b60de874840b78eaf1aa3ece8e9,

title = "Transient Increase in X-ray-induced c-Jun, c-Fos and BRCA1 Expression by Exposure to Power Frequency Magnetic Fields in MCF-7 Cells",

abstract = "The effects of Extremely Low Frequency Electromagnetic Fields (ELFMF, 50 Hz, 5 mT) and/or X-rays on the expression of the BRCA1, p21, c-Myc, c-Jun and c-Fos proteins were investigated in human breast adenocarcinoma MCF-7 cells. A transient increase of c-Jun and c-Fos was observed after either ionizing radiation or magnetic field exposure. We found that ELFMF increased the X-ray-induced expression of BRCA1, p21 and c-Myc. These findings demonstrate that ELFMF can modify gene expression.",

author = "Furong Tian and Takehisa Nakahara and Junji Miyakoshi",

year = "2005",

language = "English",

pages = "123--128",

journal = "Bulletin of Health Sciences Hirosaki Vol. 4",

}

TY - JOUR

T1 - Transient Increase in X-ray-induced c-Jun, c-Fos and BRCA1 Expression by Exposure to Power Frequency Magnetic Fields in MCF-7 Cells

AU - Tian, Furong

AU - Nakahara, Takehisa

AU - Miyakoshi, Junji

PY - 2005

Y1 - 2005

N2 - The effects of Extremely Low Frequency Electromagnetic Fields (ELFMF, 50 Hz, 5 mT) and/or X-rays on the expression of the BRCA1, p21, c-Myc, c-Jun and c-Fos proteins were investigated in human breast adenocarcinoma MCF-7 cells. A transient increase of c-Jun and c-Fos was observed after either ionizing radiation or magnetic field exposure. We found that ELFMF increased the X-ray-induced expression of BRCA1, p21 and c-Myc. These findings demonstrate that ELFMF can modify gene expression.

AB - The effects of Extremely Low Frequency Electromagnetic Fields (ELFMF, 50 Hz, 5 mT) and/or X-rays on the expression of the BRCA1, p21, c-Myc, c-Jun and c-Fos proteins were investigated in human breast adenocarcinoma MCF-7 cells. A transient increase of c-Jun and c-Fos was observed after either ionizing radiation or magnetic field exposure. We found that ELFMF increased the X-ray-induced expression of BRCA1, p21 and c-Myc. These findings demonstrate that ELFMF can modify gene expression.

UR - https://warp.da.ndl.go.jp/info:ndljp/pid/284848/www.hs.hirosaki-u.ac.jp/kouhou/yonen/pdf/HEALTHSCIENCESHIROSAKI_Vol.4.pdf

M3 - Article

SP - 123

EP - 128

JO - Bulletin of Health Sciences Hirosaki Vol. 4

JF - Bulletin of Health Sciences Hirosaki Vol. 4

ER -

Transient Increase in X-ray-induced c-Jun, c-Fos and BRCA1 Expression by Exposure to Power Frequency Magnetic Fields in MCF-7 Cells

Abstract

Fingerprint

Cite this