The use of vibrational spectroscopy to study the pathogenesis multiple sclerosis and other neurological conditions

Inês R. Ramos, Fiona M. Lyng, Ihtesham Ur Rehman, Basil Sharrack, M. Nicola Woodroofe

Research output: Contribution to journalReview articlepeer-review

Abstract

Spectroscopy techniques are valuable tools in biomedical research and have been used extensively in the study of disease. However, neurological conditions such as multiple sclerosis (MS) have received little attention and the available spectroscopy studies are limited, both in overall numbers of patients studied and the disease samples considered. MS is a complex immune-mediated disease, with variable clinical courses and limited therapeutic options. This review aims to summarize current literature in the area, demonstrating how spectroscopy techniques can provide valuable information to inform and advance research into the most common neurological condition affecting young adults.

Original languageEnglish
Pages (from-to)868-882
Number of pages15
JournalApplied Spectroscopy Reviews
Volume52
Issue number10
DOIs
Publication statusPublished - 26 Nov 2017

Keywords

  • Multiple sclerosis
  • normal-appearing white matter
  • pathology
  • spectroscopy

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