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The role of obesity in gastrointestinal cancer: Evidence and opinion

Research output: Contribution to journalReview articlepeer-review

Abstract

There is increasing recognition of the impact of being overweight and obese on the development of cancers at diverse sites including the gastrointestinal tract. Large epidemiological studies indicate that up to 14% of tumours may be related to obesity. Pathophysiological mechanisms underpinning this association are not well understood and so are discussed in this review.

Original languageEnglish
Pages (from-to)38-50
Number of pages13
JournalTherapeutic Advances in Gastroenterology
Volume7
Issue number1
DOIs
Publication statusPublished - Jan 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • adipose tissue, carcinogenesis
  • inflammation
  • signalling pathways
  • visceral adiposity

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