The effect of diameter of electronspun PGA scaffold for biological behaviour of human umbilical vein endothelial cells

Furong Tian; Hossein Hossinkhani; Yoshiro Yokoyama; Giovani Gomes Estrada; Hisatoshi Kobayashi

doi:10.4028/0-87849-436-7.237

The effect of diameter of electronspun PGA scaffold for biological behaviour of human umbilical vein endothelial cells

Furong Tian
, Hossein Hossinkhani
, Yoshiro Yokoyama
, Giovani Gomes Estrada
, Hisatoshi Kobayashi

Research output: Contribution to journal › Article › peer-review

Abstract

The objective of this work was to investigate cell adhesion, Poly Glycolic Acid (PGA) and PGA/ collagen nano-fibers on the silicone membrane. PGA with the weight-mixing ration of 40% was fabricated through the electronspun technique. The behaviors of Human Umbilical Vein Endothelial cells on these scaffolds are evaluated. The highest cell adhesion was observed in the PGA/collagen fibers with the diameter of 500 nm. This study indicates the effect of nano-fibers on the Human Umbilical Vein Endothelial cells for better understanding of interactions of cells with scaffold materials. Such information will have important implications for implantable vascular tissue engineering constructs.

Original language	English
Pages (from-to)	237-240
Number of pages	4
Journal	Key Engineering Materials
Volume	342-343
DOIs	https://doi.org/10.4028/0-87849-436-7.237
Publication status	Published - 2007
Externally published	Yes

Keywords

Collagen
Electronspinning
Human umbilical vein endothelial cells
Polyglycolic acid

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10.4028/0-87849-436-7.237

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title = "The effect of diameter of electronspun PGA scaffold for biological behaviour of human umbilical vein endothelial cells",

abstract = "The objective of this work was to investigate cell adhesion, Poly Glycolic Acid (PGA) and PGA/ collagen nano-fibers on the silicone membrane. PGA with the weight-mixing ration of 40\% was fabricated through the electronspun technique. The behaviors of Human Umbilical Vein Endothelial cells on these scaffolds are evaluated. The highest cell adhesion was observed in the PGA/collagen fibers with the diameter of 500 nm. This study indicates the effect of nano-fibers on the Human Umbilical Vein Endothelial cells for better understanding of interactions of cells with scaffold materials. Such information will have important implications for implantable vascular tissue engineering constructs.",

keywords = "Collagen, Electronspinning, Human umbilical vein endothelial cells, Polyglycolic acid",

author = "Furong Tian and Hossein Hossinkhani and Yoshiro Yokoyama and Estrada, \{Giovani Gomes\} and Hisatoshi Kobayashi",

year = "2007",

doi = "10.4028/0-87849-436-7.237",

language = "English",

volume = "342-343",

pages = "237--240",

journal = "Key Engineering Materials",

issn = "1013-9826",

publisher = "Trans Tech Publications Ltd",

}

TY - JOUR

T1 - The effect of diameter of electronspun PGA scaffold for biological behaviour of human umbilical vein endothelial cells

AU - Tian, Furong

AU - Hossinkhani, Hossein

AU - Yokoyama, Yoshiro

AU - Estrada, Giovani Gomes

AU - Kobayashi, Hisatoshi

PY - 2007

Y1 - 2007

N2 - The objective of this work was to investigate cell adhesion, Poly Glycolic Acid (PGA) and PGA/ collagen nano-fibers on the silicone membrane. PGA with the weight-mixing ration of 40% was fabricated through the electronspun technique. The behaviors of Human Umbilical Vein Endothelial cells on these scaffolds are evaluated. The highest cell adhesion was observed in the PGA/collagen fibers with the diameter of 500 nm. This study indicates the effect of nano-fibers on the Human Umbilical Vein Endothelial cells for better understanding of interactions of cells with scaffold materials. Such information will have important implications for implantable vascular tissue engineering constructs.

AB - The objective of this work was to investigate cell adhesion, Poly Glycolic Acid (PGA) and PGA/ collagen nano-fibers on the silicone membrane. PGA with the weight-mixing ration of 40% was fabricated through the electronspun technique. The behaviors of Human Umbilical Vein Endothelial cells on these scaffolds are evaluated. The highest cell adhesion was observed in the PGA/collagen fibers with the diameter of 500 nm. This study indicates the effect of nano-fibers on the Human Umbilical Vein Endothelial cells for better understanding of interactions of cells with scaffold materials. Such information will have important implications for implantable vascular tissue engineering constructs.

KW - Collagen

KW - Electronspinning

KW - Human umbilical vein endothelial cells

KW - Polyglycolic acid

UR - https://www.scopus.com/pages/publications/34147178541

U2 - 10.4028/0-87849-436-7.237

DO - 10.4028/0-87849-436-7.237

M3 - Article

AN - SCOPUS:34147178541

SN - 1013-9826

VL - 342-343

SP - 237

EP - 240

JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

The effect of diameter of electronspun PGA scaffold for biological behaviour of human umbilical vein endothelial cells

Abstract

Keywords

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