Synthesis and Spectroscopic Analysis of Therapeutic Ru(II) Complexes

Samar Moqadasi; Laura Perdisatt; Christine O'Connor; Luke O'Neill

doi:10.21427/nwfr-h927

Synthesis and Spectroscopic Analysis of Therapeutic Ru(II) Complexes

Samar Moqadasi, Laura Perdisatt, Christine O'Connor, Luke O'Neill

Technological University Dublin

Research output: Contribution to conference › Paper › peer-review

Abstract

The aim of this study is to synthesise and characterise new ligands based on a 1,10-Phenanthroline-5,6-dione backbone and their respective Ru(II) complexes; Ru(bpy)2mfmp, Ru(bpy)2fmp and Ru(bpy)2NO2-mp as shown in figure 1.The synthesis of the ligands will be discussed and a variety of Ru(II) complexes. A brief insight of the electronic and NMR spectroscopy will be presented along with preliminary photochemical results such as extinction coefficients, quantum yields and luminescence lifetimes. Ruthenium complexes have well established synthetic and photochemical properties.1The objective of this work is to synthesise Ru(II) complexes for the applications of potential therapeutics. In order to establish their uses in medicinal applications we must first ensure their purity and photochemical properties.

Original language	English
DOIs	https://doi.org/10.21427/nwfr-h927
Publication status	Published - 2009
Event	ICP2009 - Toledo, Spain Duration: 1 Jul 2009 → 31 Jul 2009

Conference

Conference	ICP2009
Country/Territory	Spain
City	Toledo
Period	1/07/09 → 31/07/09

Keywords

synthesise
characterise
ligands
Ru(II) complexes
electronic spectroscopy
NMR spectroscopy
photochemical results
extinction coefficients
quantum yields
luminescence lifetimes
therapeutics
medicinal applications
purity
photochemical properties

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title = "Synthesis and Spectroscopic Analysis of Therapeutic Ru(II) Complexes",

abstract = "The aim of this study is to synthesise and characterise new ligands based on a 1,10-Phenanthroline-5,6-dione backbone and their respective Ru(II) complexes; Ru(bpy)2mfmp, Ru(bpy)2fmp and Ru(bpy)2NO2-mp as shown in figure 1.The synthesis of the ligands will be discussed and a variety of Ru(II) complexes. A brief insight of the electronic and NMR spectroscopy will be presented along with preliminary photochemical results such as extinction coefficients, quantum yields and luminescence lifetimes. Ruthenium complexes have well established synthetic and photochemical properties.1The objective of this work is to synthesise Ru(II) complexes for the applications of potential therapeutics. In order to establish their uses in medicinal applications we must first ensure their purity and photochemical properties.",

keywords = "synthesise, characterise, ligands, Ru(II) complexes, electronic spectroscopy, NMR spectroscopy, photochemical results, extinction coefficients, quantum yields, luminescence lifetimes, therapeutics, medicinal applications, purity, photochemical properties",

author = "Samar Moqadasi and Laura Perdisatt and Christine O'Connor and Luke O'Neill",

year = "2009",

doi = "10.21427/nwfr-h927",

language = "English",

note = "ICP2009 ; Conference date: 01-07-2009 Through 31-07-2009",

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TY - CONF

T1 - Synthesis and Spectroscopic Analysis of Therapeutic Ru(II) Complexes

AU - Moqadasi, Samar

AU - Perdisatt, Laura

AU - O'Connor, Christine

AU - O'Neill, Luke

PY - 2009

Y1 - 2009

N2 - The aim of this study is to synthesise and characterise new ligands based on a 1,10-Phenanthroline-5,6-dione backbone and their respective Ru(II) complexes; Ru(bpy)2mfmp, Ru(bpy)2fmp and Ru(bpy)2NO2-mp as shown in figure 1.The synthesis of the ligands will be discussed and a variety of Ru(II) complexes. A brief insight of the electronic and NMR spectroscopy will be presented along with preliminary photochemical results such as extinction coefficients, quantum yields and luminescence lifetimes. Ruthenium complexes have well established synthetic and photochemical properties.1The objective of this work is to synthesise Ru(II) complexes for the applications of potential therapeutics. In order to establish their uses in medicinal applications we must first ensure their purity and photochemical properties.

AB - The aim of this study is to synthesise and characterise new ligands based on a 1,10-Phenanthroline-5,6-dione backbone and their respective Ru(II) complexes; Ru(bpy)2mfmp, Ru(bpy)2fmp and Ru(bpy)2NO2-mp as shown in figure 1.The synthesis of the ligands will be discussed and a variety of Ru(II) complexes. A brief insight of the electronic and NMR spectroscopy will be presented along with preliminary photochemical results such as extinction coefficients, quantum yields and luminescence lifetimes. Ruthenium complexes have well established synthetic and photochemical properties.1The objective of this work is to synthesise Ru(II) complexes for the applications of potential therapeutics. In order to establish their uses in medicinal applications we must first ensure their purity and photochemical properties.

KW - synthesise

KW - characterise

KW - ligands

KW - Ru(II) complexes

KW - electronic spectroscopy

KW - NMR spectroscopy

KW - photochemical results

KW - extinction coefficients

KW - quantum yields

KW - luminescence lifetimes

KW - therapeutics

KW - medicinal applications

KW - purity

KW - photochemical properties

U2 - 10.21427/nwfr-h927

DO - 10.21427/nwfr-h927

M3 - Paper

T2 - ICP2009

Y2 - 1 July 2009 through 31 July 2009

ER -

Synthesis and Spectroscopic Analysis of Therapeutic Ru(II) Complexes

Abstract

Conference

Keywords

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