Synthesis and characterisation of macrocycles containing both tetrazole and pyridine functionalities

Adrienne Fleming; Jackie Gaire; Fintan Kelleher; John McGinley; Vickie McKee

doi:10.1016/j.tet.2011.02.080

Synthesis and characterisation of macrocycles containing both tetrazole and pyridine functionalities

Adrienne Fleming, Jackie Gaire, Fintan Kelleher, John McGinley, Vickie McKee

School of Chemical and BioPharmaceutical Science

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The syntheses of tetra-tetrazole macrocycles containing at least one 2,6-bis(tetrazole)pyridine unit, linked by a variety of n-alkyl (n=3, 5, 7 or 9 carbon atoms) chain lengths, are described. There has been no previous incorporation of the pyridine moiety into a tetra-tetrazolophane macrocycle. The crystal structure of one such tetra-tetrazole macrocycle has also been structurally characterised and revealed a bowl-shaped conformation.

Original language	English
Pages (from-to)	3260-3266
Number of pages	7
Journal	Tetrahedron
Volume	67
Issue number	18
DOIs	https://doi.org/10.1016/j.tet.2011.02.080
Publication status	Published - 6 May 2011

Keywords

Macrocycles
Pyridine
Synthesis
Tetrazole
X-ray structure

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10.1016/j.tet.2011.02.080

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abstract = "The syntheses of tetra-tetrazole macrocycles containing at least one 2,6-bis(tetrazole)pyridine unit, linked by a variety of n-alkyl (n=3, 5, 7 or 9 carbon atoms) chain lengths, are described. There has been no previous incorporation of the pyridine moiety into a tetra-tetrazolophane macrocycle. The crystal structure of one such tetra-tetrazole macrocycle has also been structurally characterised and revealed a bowl-shaped conformation.",

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T1 - Synthesis and characterisation of macrocycles containing both tetrazole and pyridine functionalities

AU - Fleming, Adrienne

AU - Gaire, Jackie

AU - Kelleher, Fintan

AU - McGinley, John

AU - McKee, Vickie

PY - 2011/5/6

Y1 - 2011/5/6

N2 - The syntheses of tetra-tetrazole macrocycles containing at least one 2,6-bis(tetrazole)pyridine unit, linked by a variety of n-alkyl (n=3, 5, 7 or 9 carbon atoms) chain lengths, are described. There has been no previous incorporation of the pyridine moiety into a tetra-tetrazolophane macrocycle. The crystal structure of one such tetra-tetrazole macrocycle has also been structurally characterised and revealed a bowl-shaped conformation.

AB - The syntheses of tetra-tetrazole macrocycles containing at least one 2,6-bis(tetrazole)pyridine unit, linked by a variety of n-alkyl (n=3, 5, 7 or 9 carbon atoms) chain lengths, are described. There has been no previous incorporation of the pyridine moiety into a tetra-tetrazolophane macrocycle. The crystal structure of one such tetra-tetrazole macrocycle has also been structurally characterised and revealed a bowl-shaped conformation.

KW - Macrocycles

KW - Pyridine

KW - Synthesis

KW - Tetrazole

KW - X-ray structure

UR - http://www.scopus.com/inward/record.url?scp=79954417356&partnerID=8YFLogxK

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DO - 10.1016/j.tet.2011.02.080

M3 - Article

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SN - 0040-4020

VL - 67

SP - 3260

EP - 3266

JO - Tetrahedron

JF - Tetrahedron

IS - 18

ER -

Synthesis and characterisation of macrocycles containing both tetrazole and pyridine functionalities

Abstract

Keywords

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