TY - GEN
T1 - Rheological Performance of Bacterial Cellulose based Nonmineralized and Mineralized Hydrogel Scaffolds
AU - Basu, Probal
AU - Saha, Nabanita
AU - Saha, Petr
N1 - Publisher Copyright:
© 2017 Author(s).
PY - 2017
Y1 - 2017
N2 - Bacterial cellulose (BC) based hydrogels (BC-PVP and BC-CMC) are modified with β-tri-calcium phosphate (β-TCP) and hydroxyapatite (HA) to improve the structural and functional properties of the existing hydrogel scaffolds. The modified hydrogels are then biomineralized with CaCO
3 following liquid diffusion technique, where salt solutions of Na
2CO
3 (5.25 g/100 mL) and CaCl
2 (7.35 g/100 mL) were involved. The BC-PVP and BC-CMC are being compared with the non-mineralized (BC-PVP-β-TCP/HA and BC-CMC-β-TCP/HA) and biomineralized (BC-PVP-β-TCP/HA-CaCO
3 and BC-CMC-β-TCP/HA-CaCO
3) hydrogels on the basis of their structural and rheological properties. The Fourier Transform Infrared (FTIR) spectral analysis demonstrated the presence of BC, CMC, PVP, β-TCP, HA in the non-mineralized and BC, CMC, PVP, β-TCP, HA and CaCO
3 in the biomineralized samples. Interestingly, the morphological property of non-mineralized and biomineralized, hydrogels are different than that of BC-PVP and BC-CMC based novel biomaterials. The Scanning Electron Microscopic (SEM) images of the before mentioned samples reveal the denser structures than BC-PVP and BC-CMC, which exhibits the changes in their pore sizes. Concerning rheological analysis point of view, all the non-mineralized and biomineralized hydrogel scaffolds have shown significant elastic property. Additionally, the complex viscosity (η∗) values have also found in decreasing order with the increase of angular frequency (ω) 0.1 rad.sec
-1 to 100 rad.sec
-1. All these BC based hydrogel scaffolds are elastic in nature, can be recommended for their application as an implant for bone tissue engineering.
AB - Bacterial cellulose (BC) based hydrogels (BC-PVP and BC-CMC) are modified with β-tri-calcium phosphate (β-TCP) and hydroxyapatite (HA) to improve the structural and functional properties of the existing hydrogel scaffolds. The modified hydrogels are then biomineralized with CaCO
3 following liquid diffusion technique, where salt solutions of Na
2CO
3 (5.25 g/100 mL) and CaCl
2 (7.35 g/100 mL) were involved. The BC-PVP and BC-CMC are being compared with the non-mineralized (BC-PVP-β-TCP/HA and BC-CMC-β-TCP/HA) and biomineralized (BC-PVP-β-TCP/HA-CaCO
3 and BC-CMC-β-TCP/HA-CaCO
3) hydrogels on the basis of their structural and rheological properties. The Fourier Transform Infrared (FTIR) spectral analysis demonstrated the presence of BC, CMC, PVP, β-TCP, HA in the non-mineralized and BC, CMC, PVP, β-TCP, HA and CaCO
3 in the biomineralized samples. Interestingly, the morphological property of non-mineralized and biomineralized, hydrogels are different than that of BC-PVP and BC-CMC based novel biomaterials. The Scanning Electron Microscopic (SEM) images of the before mentioned samples reveal the denser structures than BC-PVP and BC-CMC, which exhibits the changes in their pore sizes. Concerning rheological analysis point of view, all the non-mineralized and biomineralized hydrogel scaffolds have shown significant elastic property. Additionally, the complex viscosity (η∗) values have also found in decreasing order with the increase of angular frequency (ω) 0.1 rad.sec
-1 to 100 rad.sec
-1. All these BC based hydrogel scaffolds are elastic in nature, can be recommended for their application as an implant for bone tissue engineering.
UR - https://www.scopus.com/pages/publications/85019748287
U2 - 10.1063/1.4983000
DO - 10.1063/1.4983000
M3 - Conference contribution
T3 - AIP Conference Proceedings
SP - 050008-1–050008-7
BT - Novel Trends in Rheology Vii
A2 - Zatloukal, Martin
ER -