Reactions of bis(tetrazole)phenylenes. Surprising formation of vinyl compounds from alkyl halides

Adrienne Fleming, Fintan Kelleher, Mary F. Mahon, John McGinley, Vipa Prajapati

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The reactions of 1,2-bis(tetrazol-5-yl)benzene (1), 1,3-bis(tetrazol-5-yl) benzene (2), 1,4-bis(tetrazol-5-yl)benzene (3), 1,2-(Bu3SnN 4C)2C6H4 (4), 1,3-(Bu 3SnN4C)2C6H4 (5) and 1,4-(Bu3SnN4C)2C6H4 (6) with 1,2-dibromoethane were carried out by two different methods in order to synthesise pendant alkyl halide derivatives of the parent bis-tetrazoles. This lead to the formation of several alkyl halide derivatives, substituted at either N1 or N2 on the tetrazole ring, as well as the surprising formation of several vinyl derivatives. The crystal structures of both 1,2-[(2-vinyl)tetrazol-5-yl)] benzene (1-N,2-N′) (1b) and 1,3-bis[(2-bromoethyl)tetrazol-5-yl]benzene (2-N,2-N′) (5d) are discussed.

    Original languageEnglish
    Pages (from-to)7002-7011
    Number of pages10
    JournalTetrahedron
    Volume61
    Issue number29
    DOIs
    Publication statusPublished - 18 Jul 2005

    Keywords

    • NMR
    • Organotin
    • Tetrazole
    • Vinyl
    • X-ray

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