Raman spectroscopic analysis of ionisation processes in biological systems

Jennifer Conroy; Eoghan Ó Faoláin; Carmel Mothersill; Colin Seymour; Fiona M. Lyng; Hugh J. Byrne

doi:10.1117/12.463638

Raman spectroscopic analysis of ionisation processes in biological systems

Jennifer Conroy, Eoghan Ó Faoláin, Carmel Mothersill, Colin Seymour, Fiona M. Lyng, Hugh J. Byrne

Radiation and Environmental Science Centre (RESC)

Research output: Contribution to journal › Conference article › peer-review

Abstract

Raman spectroscopy was employed to spectroscopically fingerprint the range of amino acids, purines and pyramidines. Irradiation of these components by 10 Gray gamma rays shows that several of the amino acids and pyrimidines are particularly prone to molecular degradation. The spectroscopic signature of the degradation is utilised to identify the molecular origin of the degradation observed in the various biological macromolecules. Irradiation in solution compared to solid state is employed in an effort to differentiate between primary and secondary ionisation processes.

Original language	English
Pages (from-to)	18-25
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4876
Issue number	1
DOIs	https://doi.org/10.1117/12.463638
Publication status	Published - 2002
Event	Opto-Ireland 2002: Optics and Photonics Technologies and Applications - Galway, Ireland Duration: 5 Sep 2002 → 6 Sep 2002

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10.1117/12.463638

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title = "Raman spectroscopic analysis of ionisation processes in biological systems",

abstract = "Raman spectroscopy was employed to spectroscopically fingerprint the range of amino acids, purines and pyramidines. Irradiation of these components by 10 Gray gamma rays shows that several of the amino acids and pyrimidines are particularly prone to molecular degradation. The spectroscopic signature of the degradation is utilised to identify the molecular origin of the degradation observed in the various biological macromolecules. Irradiation in solution compared to solid state is employed in an effort to differentiate between primary and secondary ionisation processes.",

author = "Jennifer Conroy and \{{\'O} Faol{\'a}in\}, Eoghan and Carmel Mothersill and Colin Seymour and Lyng, \{Fiona M.\} and Byrne, \{Hugh J.\}",

year = "2002",

doi = "10.1117/12.463638",

language = "English",

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pages = "18--25",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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publisher = "SPIE",

number = "1",

note = "Opto-Ireland 2002: Optics and Photonics Technologies and Applications ; Conference date: 05-09-2002 Through 06-09-2002",

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TY - JOUR

T1 - Raman spectroscopic analysis of ionisation processes in biological systems

AU - Conroy, Jennifer

AU - Ó Faoláin, Eoghan

AU - Mothersill, Carmel

AU - Seymour, Colin

AU - Lyng, Fiona M.

AU - Byrne, Hugh J.

PY - 2002

Y1 - 2002

N2 - Raman spectroscopy was employed to spectroscopically fingerprint the range of amino acids, purines and pyramidines. Irradiation of these components by 10 Gray gamma rays shows that several of the amino acids and pyrimidines are particularly prone to molecular degradation. The spectroscopic signature of the degradation is utilised to identify the molecular origin of the degradation observed in the various biological macromolecules. Irradiation in solution compared to solid state is employed in an effort to differentiate between primary and secondary ionisation processes.

AB - Raman spectroscopy was employed to spectroscopically fingerprint the range of amino acids, purines and pyramidines. Irradiation of these components by 10 Gray gamma rays shows that several of the amino acids and pyrimidines are particularly prone to molecular degradation. The spectroscopic signature of the degradation is utilised to identify the molecular origin of the degradation observed in the various biological macromolecules. Irradiation in solution compared to solid state is employed in an effort to differentiate between primary and secondary ionisation processes.

UR - https://www.scopus.com/pages/publications/0043233309

U2 - 10.1117/12.463638

DO - 10.1117/12.463638

M3 - Conference article

AN - SCOPUS:0043233309

SN - 0277-786X

VL - 4876

SP - 18

EP - 25

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

IS - 1

T2 - Opto-Ireland 2002: Optics and Photonics Technologies and Applications

Y2 - 5 September 2002 through 6 September 2002

ER -

Raman spectroscopic analysis of ionisation processes in biological systems

Abstract

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