Pristine carbon nanotube scaffolds for the growth of chondrocytes

Alice A.K. King; Brigitta Matta-Domjan; Matthew J. Large; Csaba Matta; Sean P. Ogilvie; Niki Bardi; Hugh J. Byrne; Anvar Zakhidov; Izabela Jurewicz; Eirini Velliou; Rebecca Lewis; Roberto La Ragione; Alan B. Dalton

doi:10.1039/c7tb02065a

Pristine carbon nanotube scaffolds for the growth of chondrocytes

Alice A.K. King, Brigitta Matta-Domjan, Matthew J. Large, Csaba Matta, Sean P. Ogilvie, Niki Bardi, Hugh J. Byrne, Anvar Zakhidov, Izabela Jurewicz, Eirini Velliou, Rebecca Lewis, Roberto La Ragione, Alan B. Dalton

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Abstract

The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.

Original language	English
Pages (from-to)	8178-8182
Number of pages	5
Journal	Journal of Materials Chemistry B
Volume	5
Issue number	41
DOIs	https://doi.org/10.1039/c7tb02065a
Publication status	Published - 2017

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title = "Pristine carbon nanotube scaffolds for the growth of chondrocytes",

abstract = "The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.",

author = "King, {Alice A.K.} and Brigitta Matta-Domjan and Large, {Matthew J.} and Csaba Matta and Ogilvie, {Sean P.} and Niki Bardi and Byrne, {Hugh J.} and Anvar Zakhidov and Izabela Jurewicz and Eirini Velliou and Rebecca Lewis and {La Ragione}, Roberto and Dalton, {Alan B.}",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2017.",

year = "2017",

doi = "10.1039/c7tb02065a",

language = "English",

volume = "5",

pages = "8178--8182",

journal = "Journal of Materials Chemistry B",

issn = "2050-7518",

publisher = "Royal Society of Chemistry",

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T1 - Pristine carbon nanotube scaffolds for the growth of chondrocytes

AU - King, Alice A.K.

AU - Matta-Domjan, Brigitta

AU - Large, Matthew J.

AU - Matta, Csaba

AU - Ogilvie, Sean P.

AU - Bardi, Niki

AU - Byrne, Hugh J.

AU - Zakhidov, Anvar

AU - Jurewicz, Izabela

AU - Velliou, Eirini

AU - Lewis, Rebecca

AU - La Ragione, Roberto

AU - Dalton, Alan B.

PY - 2017

Y1 - 2017

N2 - The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.

AB - The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.

UR - http://www.scopus.com/inward/record.url?scp=85032440862&partnerID=8YFLogxK

U2 - 10.1039/c7tb02065a

DO - 10.1039/c7tb02065a

M3 - Article

C2 - 32264461

AN - SCOPUS:85032440862

SN - 2050-7518

VL - 5

SP - 8178

EP - 8182

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 41

ER -

Pristine carbon nanotube scaffolds for the growth of chondrocytes

Abstract

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