Mid-infrared spectroscopic assessment of cartilage degeneration

Rubina Shaikh, Ervin Nippolainen, Vesa Virtanen, Lassi Rieppo, Julian Haas, Boris Mizaikoff, Viacheslav Artyushenko, Olga Bibikova, Isaac Afara, Simo Saarakkala, Juha Töyräs

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

We introduce classification models based on partial least squares discriminant-analysis (PLS-DA) for estimating cartilage integrity (assessed by OARSI grade) based on mid-infrared spectra of cartilage matrix. The best model achieved accuracy of 84%.

Original languageEnglish
Title of host publicationBio-Optics
Subtitle of host publicationDesign and Application - Proceedings Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA, BRAIN, NTM, OMA, OMP)
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)9781943580545
DOIs
Publication statusPublished - 8 Apr 2019
Externally publishedYes
EventBio-Optics: Design and Application, BODA 2019 - Part of Biophotonics Congress: Optics in the Life Sciences Congress 2019 - Tucson, United States
Duration: 14 Apr 201917 Apr 2019

Publication series

NameBio-Optics: Design and Application - Proceedings Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA, BRAIN, NTM, OMA, OMP)

Conference

ConferenceBio-Optics: Design and Application, BODA 2019 - Part of Biophotonics Congress: Optics in the Life Sciences Congress 2019
Country/TerritoryUnited States
CityTucson
Period14/04/1917/04/19

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