Microbial nanocellulose-based biocomposites for soft bone regeneration: From the present to the future

Probal Basu, Nabanita Saha, Tomáš Sáha, Petr Sáha

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Microbial nanocellulose (MC) draws special attention from the research community due to its unique nano-bio fabrication. This nanofiber-constructed biomaterial is biosynthesized by certain microbes in the purest form (devoid of lignin, pectin, and hemicellulose). Due to its striking similarities to animal collagen fibers, MC nanofibers have been used to develop osteoconductive biomaterial for soft tissue regeneration. High surface area, notable rheological properties, and biocompatibility make this material attractive for tissue regeneration. Concurrently, their bio-friendly characteristics are due to various bio-ceramic materials like calcium phosphate (CP) employed in conjunction with MC (for the development of scaffold/bio-composite). The significant interaction between MC's reinforcement nanofibrous matrix and the particulate fillers, such as CP, renders this biocomposite particularly intriguing. Considering the above perspectives, an effort has been made to explore and discuss the preparation and characterization of MC-CP-based biocomposites in soft bone regeneration applications. This book chapter provides a comprehensive insight into the significance of MC and biphasic calcium phosphate (BCP) based bio-composite.

Original languageEnglish
Title of host publicationEmerging Nanomaterials in Biomedical Science
PublisherNova Science Publishers, Inc.
Pages319-332
Number of pages14
ISBN (Electronic)9798895307076
ISBN (Print)9798895306000
Publication statusPublished - 17 Jul 2025

Keywords

  • Bio-composites
  • Calcium phosphate
  • Material properties
  • Microbial nanocellulose
  • Soft bone tissue regeneration

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