@inproceedings{76a26fae10c14434990150f9e4bc30e6,
title = "Label-free infrared spectroscopic imaging for characterization of necrotic tissue areas on cutaneous squamous cell carcinoma",
abstract = "In this study, FTIR spectroscopy was used to evaluate the overall biochemical status of necrotic tissue areas of cutaneous squamous cell carcinoma chemically-induced on mice. FTIR hyperspectral image collected from specimen showed high correlation with the photomicrograph obtained by light microscopy, in which we were able to identify clusters associated to keratin, necrosis and regions with no tissue. Alterations in the protein content were documented in the necrotic tissue areas, indicating changes on protein conformation.",
keywords = "Cutaneous squamous cell carcinoma, Death mechanisms, FTIR microspectroscopy, KMCA, Necrosis",
author = "Lima, \{C{\'a}ssio A.\} and Luciana Correa and Byrne, \{Hugh J.\} and Zezell, \{Denise M.\}",
note = "Publisher Copyright: {\textcopyright} 2019 SPIE.; Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVII 2019 ; Conference date: 03-02-2019 Through 05-02-2019",
year = "2019",
doi = "10.1117/12.2510711",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Grundfest, \{Warren S.\} and Anita Mahadevan-Jansen",
booktitle = "Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVII",
address = "United States",
}