Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase

Muhammad Akram, Melanie Patt, Teresa Kaserer, Veronika Temml, Watcharee Waratchareeyakul, Denise V. Kratschmar, Joerg Haupenthal, Rolf W. Hartmann, Alex Odermatt, Daniela Schuster

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number105358
JournalJournal of Steroid Biochemistry and Molecular Biology
Volume192
DOIs
Publication statusPublished - Sep 2019
Externally publishedYes

Keywords

  • Aldosterone synthase
  • Cortisol synthase
  • Endocrine disruption
  • Environmental chemical
  • Fungicide
  • Pharmacophore modeling
  • Steroidogenesis
  • Virtual screening

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