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Enterobacter sakazakii: an emerging microbe with implications for infant health

  • Niall R. Mullane
  • , Brendan Healy
  • , Ciara Walsh
  • , Carol Iversen
  • , Paul Whyte
  • , Patrick Wall
  • , Teresa Quinn
  • , Seamus Fanning

Research output: Contribution to journal › Article › peer-review

Abstract

Enterobacter sakazakii is a motile peritrichous, Gram-negative non-spore
forming facultative anaerobic bacillus belonging to the family
Enterobacteriaceae, genus Enterobacter. The microbe was listed as a new
species in 1980 . Using DNA-DNA hybridisation and biochemical tests
Farmer et al. defined the species and identified fifteen distinct biogroups[1]
with a new biogroup being added recently[2]. Based on genotyping and
biotyping E. sakazakii represents a genetically diverse and taxonomically ill-
defined species.
Enterobacter sakazakii is recognised as an emerging opportunistic pathogen
and is the aetiological agent in rare cases of meningitis, necrotising
enterocolitis and bacteremia in infants[6-15]. Since the first case of meningitis
in an infant iwas described in England in 1958[16], neonatal infections
involving E. sakazakii have been reported from all parts of the developing
world with many of these resulting in the deaths of more than seventy infants
Original languageEnglish (Ireland)
Article number59
Pages (from-to)137-148
Number of pages11
JournalMinerva paediatrica review
Volume59
Publication statusPublished - 2007

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