Abstract
Prions are infectious proteins that are responsible for a number of mammalian degenerative diseases. The discovery of prions in yeast has allowed detailed genetic analysis to be carried out to identify cellular factors involved in prion propagation. It is now clear that a complex relationship exists between molecular chaper-ones and prion propagation. Prions may actually have evolved to exploit the cell's chaperone machinery to ensure their own propagation.
| Original language | English |
|---|---|
| Pages (from-to) | 6-10 |
| Number of pages | 5 |
| Journal | Bio Tech International |
| Volume | 18 |
| Issue number | 1 |
| Publication status | Published - Feb 2006 |