Carcinogenesis in prostate cancer: The role of long non-coding RNAs

John Aird; Anne Marie Baird; Marvin C.J. Lim; Ray McDermott; Stephen P. Finn; Steven G. Gray

doi:10.1016/j.ncrna.2018.01.001

Carcinogenesis in prostate cancer: The role of long non-coding RNAs

John Aird, Anne Marie Baird, Marvin C.J. Lim, Ray McDermott, Stephen P. Finn, Steven G. Gray

Research output: Contribution to journal › Review article › peer-review

Abstract

LncRNAs appear to play a considerable role in tumourigenesis through regulating key processes in cancer cells such as proliferative signalling, replicative immortality, invasion and metastasis, evasion of growth suppressors, induction of angiogenesis and resistance to apoptosis. LncRNAs have been reported to play a role in prostate cancer, particularly in regulating the androgen receptor signalling pathway. In this review article, we summarise the role of 34 lncRNAs in prostate cancer with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.

Original language	English
Pages (from-to)	29-38
Number of pages	10
Journal	Non-coding RNA Research
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/j.ncrna.2018.01.001
Publication status	Published - Mar 2018
Externally published	Yes

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https://arrow.tudublin.ie/scschbioart/196Licence: CC BY-NC-ND

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title = "Carcinogenesis in prostate cancer: The role of long non-coding RNAs",

abstract = "LncRNAs appear to play a considerable role in tumourigenesis through regulating key processes in cancer cells such as proliferative signalling, replicative immortality, invasion and metastasis, evasion of growth suppressors, induction of angiogenesis and resistance to apoptosis. LncRNAs have been reported to play a role in prostate cancer, particularly in regulating the androgen receptor signalling pathway. In this review article, we summarise the role of 34 lncRNAs in prostate cancer with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.",

author = "John Aird and Baird, \{Anne Marie\} and Lim, \{Marvin C.J.\} and Ray McDermott and Finn, \{Stephen P.\} and Gray, \{Steven G.\}",

note = "Publisher Copyright: {\textcopyright} 2018 The Authors",

year = "2018",

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doi = "10.1016/j.ncrna.2018.01.001",

language = "English",

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T2 - The role of long non-coding RNAs

AU - Aird, John

AU - Baird, Anne Marie

AU - Lim, Marvin C.J.

AU - McDermott, Ray

AU - Finn, Stephen P.

AU - Gray, Steven G.

PY - 2018/3

Y1 - 2018/3

N2 - LncRNAs appear to play a considerable role in tumourigenesis through regulating key processes in cancer cells such as proliferative signalling, replicative immortality, invasion and metastasis, evasion of growth suppressors, induction of angiogenesis and resistance to apoptosis. LncRNAs have been reported to play a role in prostate cancer, particularly in regulating the androgen receptor signalling pathway. In this review article, we summarise the role of 34 lncRNAs in prostate cancer with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.

AB - LncRNAs appear to play a considerable role in tumourigenesis through regulating key processes in cancer cells such as proliferative signalling, replicative immortality, invasion and metastasis, evasion of growth suppressors, induction of angiogenesis and resistance to apoptosis. LncRNAs have been reported to play a role in prostate cancer, particularly in regulating the androgen receptor signalling pathway. In this review article, we summarise the role of 34 lncRNAs in prostate cancer with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.

UR - https://www.scopus.com/pages/publications/85061210581

U2 - 10.1016/j.ncrna.2018.01.001

DO - 10.1016/j.ncrna.2018.01.001

M3 - Review article

SN - 2468-0540

VL - 3

SP - 29

EP - 38

JO - Non-coding RNA Research

JF - Non-coding RNA Research

IS - 1

ER -

Carcinogenesis in prostate cancer: The role of long non-coding RNAs

Abstract

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