Carbon Nanomaterials-Based Drug Delivery Systems: Synthesis, DFT Drug Interactions, and Cancer Therapy

Over the past decades, carbon nanomaterials (CNMs) have attracted the scientific community's interest owing to their extraordinary physical properties, versatile chemical modifications, and biocompatibility. CNMs have demonstrated a high affinity for tumor sites while also controlling drug release, improving therapeutic efficiency and reducing side effects to surrounding normal tissues. Besides, CNMs have enhanced the response to immunotherapy treatments. In this chapter, the different CNM synthesis techniques, functionalization, and characterizations will be demonstrated. The recent applications of CNMs for drug delivery and cancer therapy will be the major focus. The CNMs' toxicity concerns and interactions with cells will be covered. The recent theoretical studies on the interaction between the CNMs and the most widely used anticancer drugs to better predict and understand their adsorption properties, including loading and release conditions, will be briefly discussed.