Bionanomaterials for cancer therapy

Monireh Ganjali, Mansoureh Ganjali, Mohammad Mahdi Adib Sereshki, Navid Ahmadinasab, Arash Ghalandarzadeh, Alaa A.A. Aljabali, Ahmed Barhoum

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Cancer is the second leading cause of death worldwide after cardiovascular disease. The mortality rate of cancer has been reduced in recent times due to early diagnosis and effective therapy. Cancer treatment depends on the kind of cancer, including chemotherapy, radiation therapy, surgical intervention, or a combination of these options. Regular chemotherapy is a treatment of the disease that obliterates malignant cells with drugs and stops the growth or proliferation of these cells. Despite the apparent benefits of chemotherapy, there are several disadvantages, including lack of efficacy in the long-term outcome because they failed to target cancer cells and toxicity due to nonspecific effects on normal cells. Thus, this chapter focuses on a new generation of medicine based on polymeric nanocomposites for the chemo drug carriers by controlling the release rate of the loaded drug over a prolonged period and reducing side effects of anticancer drugs.

Original languageEnglish
Title of host publicationBionanotechnology
Subtitle of host publicationEmerging Applications of Bionanomaterials
PublisherElsevier
Pages443-468
Number of pages26
ISBN (Electronic)9780128239155
ISBN (Print)9780128242209
DOIs
Publication statusPublished - 1 Jan 2022

Keywords

  • Cancer
  • Drug delivery
  • Nanotechnology
  • Polymeric nanocomposites

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