Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Cassio A. Lima; Luciana Correa; Hugh J. Byrne; Denise M. Zezell

doi:10.1117/12.2527137

Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Cassio A. Lima
, Luciana Correa
, Hugh J. Byrne
, Denise M. Zezell

Physical to Life Sciences Research Hub

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.

Original language	English
Title of host publication	European Conference on Biomedical Optics, ECBO_2019
Publisher	Optica Publishing Group (formerly OSA)
ISBN (Print)	9781510628397
DOIs	https://doi.org/10.1117/12.2527137
Publication status	Published - 2019
Event	European Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands Duration: 23 Jun 2019 → 25 Jun 2019

Publication series

Name	Optics InfoBase Conference Papers
Volume	Part F142-ECBO 2019
ISSN (Electronic)	2162-2701

Conference

Conference	European Conference on Biomedical Optics, ECBO_2019
Country/Territory	Netherlands
City	Munich
Period	23/06/19 → 25/06/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

FTIR microspectroscopy
Image reconstruction
K-means clustering analysis
Skin imaging

Access to Document

10.1117/12.2527137

Cite this

@inproceedings{16b3695917fb4daba1ade345d23dd9ff,

title = "Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy",

abstract = "Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.",

keywords = "FTIR microspectroscopy, Image reconstruction, K-means clustering analysis, Skin imaging",

author = "Lima, \{Cassio A.\} and Luciana Correa and Byrne, \{Hugh J.\} and Zezell, \{Denise M.\}",

note = "Publisher Copyright: {\textcopyright} SPIE-OSA 2019; European Conference on Biomedical Optics, ECBO\_2019 ; Conference date: 23-06-2019 Through 25-06-2019",

year = "2019",

doi = "10.1117/12.2527137",

language = "English",

isbn = "9781510628397",

series = "Optics InfoBase Conference Papers",

publisher = "Optica Publishing Group (formerly OSA)",

booktitle = "European Conference on Biomedical Optics, ECBO\_2019",

address = "United States",

}

Lima, CA, Correa, L, Byrne, HJ & Zezell, DM 2019, Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy. in European Conference on Biomedical Optics, ECBO_2019. Optics InfoBase Conference Papers, vol. Part F142-ECBO 2019, Optica Publishing Group (formerly OSA), European Conference on Biomedical Optics, ECBO_2019, Munich, Netherlands, 23/06/19. https://doi.org/10.1117/12.2527137

Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy. / Lima, Cassio A.; Correa, Luciana; Byrne, Hugh J. et al.
European Conference on Biomedical Optics, ECBO_2019. Optica Publishing Group (formerly OSA), 2019. (Optics InfoBase Conference Papers; Vol. Part F142-ECBO 2019).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

AU - Lima, Cassio A.

AU - Correa, Luciana

AU - Byrne, Hugh J.

AU - Zezell, Denise M.

PY - 2019

Y1 - 2019

N2 - Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.

AB - Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.

KW - FTIR microspectroscopy

KW - Image reconstruction

KW - K-means clustering analysis

KW - Skin imaging

UR - https://www.scopus.com/pages/publications/85084490988

U2 - 10.1117/12.2527137

DO - 10.1117/12.2527137

M3 - Conference contribution

AN - SCOPUS:85084490988

SN - 9781510628397

T3 - Optics InfoBase Conference Papers

BT - European Conference on Biomedical Optics, ECBO_2019

PB - Optica Publishing Group (formerly OSA)

T2 - European Conference on Biomedical Optics, ECBO_2019

Y2 - 23 June 2019 through 25 June 2019

ER -

Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

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Cite this