Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Cassio A. Lima; Luciana Correa; Hugh J. Byrne; Denise M. Zezell

doi:10.1117/12.2527137

Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Cassio A. Lima
, Luciana Correa
, Hugh J. Byrne
, Denise M. Zezell

Physical to Life Sciences Research Hub

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.

Original language	English
Title of host publication	Clinical and Preclinical Optical Diagnostics II
Editors	J. Quincy Brown, Ton G. van Leeuwen
Publisher	SPIE
ISBN (Electronic)	9781510628397
DOIs	https://doi.org/10.1117/12.2527137
Publication status	Published - 2019
Event	Clinical and Preclinical Optical Diagnostics II 2019 - Munich, Germany Duration: 23 Jun 2019 → 25 Jun 2019

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	11073
ISSN (Print)	1605-7422

Conference

Conference	Clinical and Preclinical Optical Diagnostics II 2019
Country/Territory	Germany
City	Munich
Period	23/06/19 → 25/06/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

FTIR microspectroscopy
Image reconstruction
K-means clustering analysis
Skin imaging

Access to Document

10.1117/12.2527137

Cite this

Lima, C. A., Correa, L., Byrne, H. J., & Zezell, D. M. (2019). Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy. In J. Q. Brown, & T. G. van Leeuwen (Eds.), Clinical and Preclinical Optical Diagnostics II Article 110730S (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11073). SPIE. https://doi.org/10.1117/12.2527137

@inproceedings{7a0db1b8d5e841fbb2c423b3a18616da,

title = "Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy",

abstract = "Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.",

keywords = "FTIR microspectroscopy, Image reconstruction, K-means clustering analysis, Skin imaging",

author = "Lima, \{Cassio A.\} and Luciana Correa and Byrne, \{Hugh J.\} and Zezell, \{Denise M.\}",

note = "Publisher Copyright: {\textcopyright} 2019 SPIE.; Clinical and Preclinical Optical Diagnostics II 2019 ; Conference date: 23-06-2019 Through 25-06-2019",

year = "2019",

doi = "10.1117/12.2527137",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Brown, \{J. Quincy\} and \{van Leeuwen\}, \{Ton G.\}",

booktitle = "Clinical and Preclinical Optical Diagnostics II",

address = "United States",

}

Lima, CA, Correa, L, Byrne, HJ & Zezell, DM 2019, Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy. in JQ Brown & TG van Leeuwen (eds), Clinical and Preclinical Optical Diagnostics II., 110730S, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 11073, SPIE, Clinical and Preclinical Optical Diagnostics II 2019, Munich, Germany, 23/06/19. https://doi.org/10.1117/12.2527137

Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy. / Lima, Cassio A.; Correa, Luciana; Byrne, Hugh J. et al.
Clinical and Preclinical Optical Diagnostics II. ed. / J. Quincy Brown; Ton G. van Leeuwen. SPIE, 2019. 110730S (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11073).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

AU - Lima, Cassio A.

AU - Correa, Luciana

AU - Byrne, Hugh J.

AU - Zezell, Denise M.

PY - 2019

Y1 - 2019

N2 - Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.

AB - Fourier Transform Infrared (FTIR) spectroscopy is a label-free analytical technique used to evaluate the chemical profile of a sample based on its molecular vibrations. The potential dermatological applications of FTIR spectroscopy has been well demonstrated over the past decades through many proof-of-concept studies evaluating cancerous and non-cancerous cutaneous diseases. Considering that the correctly identification of skin components plays an important role in the study of cutaneous diseases, the present study aims to evaluate the spectrochemical signatures of dermis and epidermis based on the pixels of a FTIR hyperspectral image collected from healthy skin.

KW - FTIR microspectroscopy

KW - Image reconstruction

KW - K-means clustering analysis

KW - Skin imaging

UR - https://www.scopus.com/pages/publications/85073747595

U2 - 10.1117/12.2527137

DO - 10.1117/12.2527137

M3 - Conference contribution

AN - SCOPUS:85073747595

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Clinical and Preclinical Optical Diagnostics II

A2 - Brown, J. Quincy

A2 - van Leeuwen, Ton G.

PB - SPIE

T2 - Clinical and Preclinical Optical Diagnostics II 2019

Y2 - 23 June 2019 through 25 June 2019

ER -

Assessing the spectrochemical signatures of skin components using FTIR microspectroscopy

Abstract

Publication series

Conference

UN SDGs

Keywords

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