Antibody-based sensors: Principles, problems and potential for detection of pathogens and associated toxins

Barry Byrne, Edwina Stack, Niamh Gilmartin, Richard O'Kennedy

Research output: Contribution to journalReview articlepeer-review

Abstract

Antibody-based sensors permit the rapid and sensitive analysis of a range of pathogens and associated toxins. A critical assessment of the implementation of such formats is provided, with reference to their principles, problems and potential for 'on-site' analysis. Particular emphasis is placed on the detection of foodborne bacterial pathogens, such as Escherichia coli and Listeria monocytogenes, and additional examples relating to the monitoring of fungal pathogens, viruses, mycotoxins, marine toxins and parasites are also provided.

Original languageEnglish
Pages (from-to)4407-4445
Number of pages39
JournalSensors (Switzerland)
Volume9
Issue number6
DOIs
Publication statusPublished - Jun 2009

Keywords

  • Antibody
  • Assay development
  • Biosensor
  • Electrochemical
  • Pathogen
  • Surface-plasmon resonance

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