Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food

B. Byrne; N. Gilmartin; R. S. Lakshmanan; R. O'Kennedy

doi:10.1016/B978-0-85709-801-6.00003-4

Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food

B. Byrne, N. Gilmartin, R. S. Lakshmanan, R. O'Kennedy

School of Biological, Health and Sports Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

It is well established that the contamination of produce destined for human consumption by pathogenic microbes and/or toxins poses a considerable risk to public health and has serious economic consequences. Hence, it is imperative that such analytes are detected through the implementation of rapid, reproducible, and sensitive detection strategies. In this chapter, we provide a critical assessment of three methodologies that incorporate antibody-, enzyme-, or nucleic acid-based probes as biorecognition elements and discuss how these can be applied for high throughput screening of pathogens and toxins in complex food sample matrices.

Original language	English
Title of host publication	High Throughput Screening for Food Safety Assessment
Subtitle of host publication	Biosensor Technologies, Hyperspectral Imaging and Practical Applications
Publisher	Elsevier Inc.
Pages	25-80
Number of pages	56
ISBN (Electronic)	9780857098078
ISBN (Print)	9780857098016
DOIs	https://doi.org/10.1016/B978-0-85709-801-6.00003-4
Publication status	Published - 2015

Keywords

Antibodies
Array
Enzyme
Immunosensors
Multiplexed detection
Nucleic acid
Pathogen
Toxin

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-85709-801-6.00003-4

Cite this

Byrne, B., Gilmartin, N., Lakshmanan, R. S., & O'Kennedy, R. (2015). Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food. In High Throughput Screening for Food Safety Assessment: Biosensor Technologies, Hyperspectral Imaging and Practical Applications (pp. 25-80). Elsevier Inc.. https://doi.org/10.1016/B978-0-85709-801-6.00003-4

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title = "Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food",

abstract = "It is well established that the contamination of produce destined for human consumption by pathogenic microbes and/or toxins poses a considerable risk to public health and has serious economic consequences. Hence, it is imperative that such analytes are detected through the implementation of rapid, reproducible, and sensitive detection strategies. In this chapter, we provide a critical assessment of three methodologies that incorporate antibody-, enzyme-, or nucleic acid-based probes as biorecognition elements and discuss how these can be applied for high throughput screening of pathogens and toxins in complex food sample matrices.",

keywords = "Antibodies, Array, Enzyme, Immunosensors, Multiplexed detection, Nucleic acid, Pathogen, Toxin",

author = "B. Byrne and N. Gilmartin and Lakshmanan, \{R. S.\} and R. O'Kennedy",

year = "2015",

doi = "10.1016/B978-0-85709-801-6.00003-4",

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isbn = "9780857098016",

pages = "25--80",

booktitle = "High Throughput Screening for Food Safety Assessment",

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Byrne, B, Gilmartin, N, Lakshmanan, RS & O'Kennedy, R 2015, Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food. in High Throughput Screening for Food Safety Assessment: Biosensor Technologies, Hyperspectral Imaging and Practical Applications. Elsevier Inc., pp. 25-80. https://doi.org/10.1016/B978-0-85709-801-6.00003-4

Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food. / Byrne, B.; Gilmartin, N.; Lakshmanan, R. S. et al.
High Throughput Screening for Food Safety Assessment: Biosensor Technologies, Hyperspectral Imaging and Practical Applications. Elsevier Inc., 2015. p. 25-80.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food

AU - Byrne, B.

AU - Gilmartin, N.

AU - Lakshmanan, R. S.

AU - O'Kennedy, R.

PY - 2015

Y1 - 2015

N2 - It is well established that the contamination of produce destined for human consumption by pathogenic microbes and/or toxins poses a considerable risk to public health and has serious economic consequences. Hence, it is imperative that such analytes are detected through the implementation of rapid, reproducible, and sensitive detection strategies. In this chapter, we provide a critical assessment of three methodologies that incorporate antibody-, enzyme-, or nucleic acid-based probes as biorecognition elements and discuss how these can be applied for high throughput screening of pathogens and toxins in complex food sample matrices.

AB - It is well established that the contamination of produce destined for human consumption by pathogenic microbes and/or toxins poses a considerable risk to public health and has serious economic consequences. Hence, it is imperative that such analytes are detected through the implementation of rapid, reproducible, and sensitive detection strategies. In this chapter, we provide a critical assessment of three methodologies that incorporate antibody-, enzyme-, or nucleic acid-based probes as biorecognition elements and discuss how these can be applied for high throughput screening of pathogens and toxins in complex food sample matrices.

KW - Antibodies

KW - Array

KW - Enzyme

KW - Immunosensors

KW - Multiplexed detection

KW - Nucleic acid

KW - Pathogen

KW - Toxin

UR - https://www.scopus.com/pages/publications/84942925955

U2 - 10.1016/B978-0-85709-801-6.00003-4

DO - 10.1016/B978-0-85709-801-6.00003-4

M3 - Chapter

AN - SCOPUS:84942925955

SN - 9780857098016

SP - 25

EP - 80

BT - High Throughput Screening for Food Safety Assessment

PB - Elsevier Inc.

ER -

Antibodies, enzymes, and nucleic acid sensors for high throughput screening of microbes and toxins in food

Abstract

Keywords

UN SDGs

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