TY - JOUR
T1 - A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases
AU - Hunt, Mary C.
AU - Yamada, Junji
AU - Maltais, Lois J.
AU - Wright, Mathew W.
AU - Podesta, Ernesto J.
AU - Alexson, Stefan E.H.
PY - 2005/9
Y1 - 2005/9
N2 - Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA esters such as acyl-CoAs (saturated, unsaturated, branched-chain), bile acid-CoAs, CoA esters of prostaglandins, etc., to the corresponding free acid and CoA. However, there is significant confusion regarding the nomenclature of these genes. In agreement with the HUGO Gene Nomenclature Committee and the Mouse Genomic Nomenclature Committee, a revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases has been suggested for the 12 member family. The family root symbol is ACOT, with human genes named ACOT1-ACOT12, and rat and mouse genes named Acot1-Acot12. Several of the ACOT genes are the result of splicing events, and these splice variants are cataloged.
AB - Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA esters such as acyl-CoAs (saturated, unsaturated, branched-chain), bile acid-CoAs, CoA esters of prostaglandins, etc., to the corresponding free acid and CoA. However, there is significant confusion regarding the nomenclature of these genes. In agreement with the HUGO Gene Nomenclature Committee and the Mouse Genomic Nomenclature Committee, a revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases has been suggested for the 12 member family. The family root symbol is ACOT, with human genes named ACOT1-ACOT12, and rat and mouse genes named Acot1-Acot12. Several of the ACOT genes are the result of splicing events, and these splice variants are cataloged.
KW - Coenzyme A
KW - Fatty acid metabolism
KW - Peroxisomes
UR - https://www.scopus.com/pages/publications/24344476275
U2 - 10.1194/jlr.E500003-JLR200
DO - 10.1194/jlr.E500003-JLR200
M3 - Article
C2 - 16103133
AN - SCOPUS:24344476275
SN - 0022-2275
VL - 46
SP - 2029
EP - 2032
JO - Journal of Lipid Research
JF - Journal of Lipid Research
IS - 9
ER -