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A large-scale CNN ensemble for medication safety analysis

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Revealing Adverse Drug Reactions (ADR) is an essential part of post-marketing drug surveillance, and data from health-related forums and medical communities can be of a great significance for estimating such effects. In this paper, we propose an end-to-end CNN-based method for predicting drug safety on user comments from healthcare discussion forums. We present an architecture that is based on a vast ensemble of CNNs with varied structural parameters, where the prediction is determined by the majority vote. To evaluate the performance of the proposed solution, we present a large-scale dataset collected from a medical website that consists of over 50 thousand reviews for more than 4000 drugs. The results demonstrate that our model significantly outperforms conventional approaches and predicts medicine safety with an accuracy of 87.17% for binary and 62.88% for multi-classification tasks.

Original languageEnglish
Title of host publicationNatural Language Processing and Information Systems - 22nd International Conference on Applications of Natural Language to Information Systems, NLDB 2017, Proceedings
EditorsFlavius Frasincar, Ashwin Ittoo, Elisabeth Metais, Le Minh Nguyen
PublisherSpringer Verlag
Pages247-253
Number of pages7
ISBN (Print)9783319595689
DOIs
Publication statusPublished - 2017
Event22nd International Conference on Applications of Natural Language to Information Systems, NLDB 2017 - Liege, Belgium
Duration: 21 Jun 201723 Jun 2017

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume10260 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference22nd International Conference on Applications of Natural Language to Information Systems, NLDB 2017
Country/TerritoryBelgium
CityLiege
Period21/06/1723/06/17

Keywords

  • Adverse Drug Reactions
  • Convolutional Neural Networks
  • Deep learning
  • Ensembles
  • Sentiment analysis

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