Project Details
Description
This project focuses on the MedDevDoc Doctoral Scholarship program to support a PhD research student at TU Dublin for four years. This program is offered by the SFI Centre CURAM, funded by the HORIZON-MSCA-2022-COFUND scheme.
PhD Project Description:
High-Intensity Focused Ultrasound (HIFU) is an emerging therapy using high-intensity sound waves for tissue ablation, drug delivery, and disruption of the blood-brain barrier. Ultrasound beams target a localized tissue area, producing therapeutic thermal and mechanical effects. Accurate characterization of the HIFU beam intensity and focal point is essential but challenging in clinical settings.
The objectives of this PhD project are:
- Develop a novel optical sensor to characterize the HIFU field.
- Evaluate the sensor’s ability to aid in planning and verifying HIFU therapies.
The proposed sensor is a photopolymer film-based holographic diffraction grating optimized to show a quantifiable visual color change when exposed to precise HIFU doses. The sensor's response to HIFU frequency, intensity, and focus will be systematically investigated during a placement at INRiM, the Italian Metrological Institute. A clinical prototype will be developed through testing on MR-guided HIFU systems in collaboration with the Mayo Clinic, USA.
PhD Project Description:
High-Intensity Focused Ultrasound (HIFU) is an emerging therapy using high-intensity sound waves for tissue ablation, drug delivery, and disruption of the blood-brain barrier. Ultrasound beams target a localized tissue area, producing therapeutic thermal and mechanical effects. Accurate characterization of the HIFU beam intensity and focal point is essential but challenging in clinical settings.
The objectives of this PhD project are:
- Develop a novel optical sensor to characterize the HIFU field.
- Evaluate the sensor’s ability to aid in planning and verifying HIFU therapies.
The proposed sensor is a photopolymer film-based holographic diffraction grating optimized to show a quantifiable visual color change when exposed to precise HIFU doses. The sensor's response to HIFU frequency, intensity, and focus will be systematically investigated during a placement at INRiM, the Italian Metrological Institute. A clinical prototype will be developed through testing on MR-guided HIFU systems in collaboration with the Mayo Clinic, USA.
| Status | Active |
|---|---|
| Effective start/end date | 1/12/23 → 30/11/28 |
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