Personal profile
Research Interests
PhD with Trinity College Dublin in 2000-2004, in conjunction with the Queensland Institute of Medical Research in Brisbane, Australia (2002-2004). Awarded a DIT Arnold Graves postdoctoral fellowship in 2005 to conduct research until 2008 in the RESC and received a scholar in Training (SIT) award with the Radiation Research Society in Sept 2008 for part of this work. Recipient of several early career researcher awards during postgraduate and postdoctoral research. Moved to an academic post as assistant Lecturer of cell biology/biology in 2009, progressed to Lecturer grade in 2013 and then senior Lecturer grade 1 (SL1) in 2016 with the School of Biological and Health Sciences in Dublin Institute of Technology. Later awarded an honorary professorship in 2017 by DIT. Currently working in the School of Biological, Health and Sports Sciences in TUDublin as a senior lecturer and researcher, with her own research group.
Professional Information
>24 years of academic career in research and teaching at 3rd level. She has supervised >25 postgraduate students to completion (98% at PhD level), currently supervising 8 PhD students (primary supervisor for 4 in designated research group in the area of radiaton therapy and therapeutics). She has examined and chaired >30 and >25 respectviely PhD and MPhil students at viva voce. She is the founder and current vice president of the Irish Biological Inorganic Chemistry Society (IBICS) in 2024 having previously fulfillied her duties as honorary treasurer (2017-2022) and honorary secretary (2017-2023) of IBICS. She is also a member of SBIC and EuroBIC, and involved in organising the annual scientific symposium for IBICS. She has been involved in many multidisciplinary research projects within TUDublin, cross national universities and major European projects including EU FP6, FP7 and the current MSCA Bicyclos consortium project (2024). She has close international research collaborations and links with Brazil and Canada for various projects. She has obtained additional funding for research through the HEA IRC, SFI, TSR Strand I, and others. In recent years, she was also awarded a TUDublin Researcher award (2021) and was nominated by her postgraduate students for a Reseach and Innovation Excellence award in postgraduate supervision in 2024.
Research Interests are in Radiobiology, therapeutics (both Inorganic and organic molecules) and targeted-therapies using knowledge and expertise in complex cellular signalling pathways, molecular technologies, in vitro and in vivo work.
Education/Academic qualification
PhD
Award Date: 1 Jan 2005
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Collaborations and top research areas from the last five years
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Raman spectroscopic profiling of cell death induced by cytotoxic copper(II), manganese(II), and silver(I) complexes containing dicarboxylate and 1,10-phenanthroline ligands: novel insights into in vitro mechanisms
O’Sullivan, E., O’Shea, D., Devereux, M., Howe, O. & Byrne, H. J., 1 Jan 2026, In: Metallomics. 18, 1, mfaf044.Research output: Contribution to journal › Article › peer-review
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An Alternative Method to Measure Glucose and Lactic Acid as Biomarkers of the Postmortem Interval (PMI)
Tersaruolo, C., Frias, J. & Howe, O., Jun 2025, In: Forensic Sciences. 5, 2, 17.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Apoptotic cell death induced by copper (II), manganese (II) and silver (I) complexes containing bridging dicarboxylate and 1,10-phenanthroline ligands: one of the multi-modes of anticancer activity?
O’Sullivan, E., O’Shea, D., Devereux, M. & Howe, O., Jun 2025, In: BioMetals. 38, 3, p. 785-805 21 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Apoptotic cell death induced by copper (II), manganese (II) and silver (I) complexes containing bridging dicarboxylate and 1,10-phenanthroline ligands: one of the multi-modes of anticancer activity?
O’Sullivan, E., O’Shea, D., Devereux, M. & Howe, O., Jun 2025, In: BioMetals.Research output: Contribution to journal › Article › peer-review
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Autophagy-dependent cell death and immune responses induced by heteroleptic copper(II), manganese(II), and silver(I) complexes containing dicarboxylate and 1,10-phenanthroline ligands: novel insights from in vitro and in vivo models
O’Sullivan, E., O’Shea, D., Devereux, M., Kavanagh, K. & Howe, O., 2025, (Accepted/In press) In: BioMetals.Research output: Contribution to journal › Article › peer-review
Prizes
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- 9th International Congress of Radiation Research (ICRR) organizer award, 1999
Howe, O. (Recipient), 1 Jun 1999
Prize
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Nomination for R&I excellence award in postgraduate supervision
Howe, O. (Recipient), Sep 2023
Prize: Other distinction
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Nomination for TUDublin R&I Award for excellence in Research Supervision
Howe, O. (Recipient), Nov 2023
Prize: Honorary award
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Nomination for TUDublin R&I Award for excellence in Research Supervision
Howe, O. (Recipient), 3 Nov 2025
Prize: Honorary award
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Nomination for TUDublin R&I Multidisciplinary Team Award
Howe, O. (Recipient), 4 Nov 2024
Prize: Honorary award